Richard A Flavell Selected Research

Interleukin-9 (Interleukin 9)

1/2022	An IL-9-pulmonary macrophage axis defines the allergic lung inflammatory environment.
1/2022	Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9.
1/2022	Allergic airway recall responses require IL-9 from resident memory CD4+ T cells.
1/2022	CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of TH1 and TH9 cells.
1/2021	IL-4-BATF signaling directly modulates IL-9 producing mucosal mast cell (MMC9) function in experimental food allergy.
7/2014	IL-9 regulates allergen-specific Th1 responses in allergic contact dermatitis.
10/2013	Th9 Cells Drive Host Immunity against Gastrointestinal Worm Infection.
1/2007	IL9 leads to airway inflammation by inducing IL13 expression in airway epithelial cells.
1/2002	Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology.

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Richard A Flavell Research Topics

Disease

83	Inflammation (Inflammations) 01/2022 - 11/2002
78	Infections 04/2022 - 06/2002
46	Neoplasms (Cancer) 01/2022 - 03/2002
28	Colitis 01/2022 - 02/2002
21	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 12/2002
18	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 04/2006
17	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2018 - 08/2002
15	Virus Diseases (Viral Diseases) 01/2022 - 03/2004
14	Asthma (Bronchial Asthma) 01/2022 - 01/2002
10	Ischemia 11/2021 - 11/2002
10	Carcinogenesis 10/2020 - 08/2003
9	Pneumonia (Pneumonitis) 04/2022 - 01/2002
9	Insulin Resistance 01/2022 - 03/2004
9	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2022 - 08/2002
9	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2016 - 06/2003
8	Fibrosis (Cirrhosis) 01/2022 - 12/2002
8	Obesity 12/2021 - 10/2007
7	Arthritis (Polyarthritis) 01/2020 - 06/2002
7	Atherosclerosis 10/2014 - 11/2003
7	Encephalitis (Encephalitis, Rasmussen) 01/2012 - 12/2004
6	Melanoma (Melanoma, Malignant) 01/2022 - 05/2006
6	Hypersensitivity (Allergy) 01/2021 - 02/2002
6	Bacterial Infections (Bacterial Infection) 01/2019 - 07/2002
6	West Nile Fever 01/2017 - 12/2004
6	Lung Injury 07/2012 - 01/2003
6	Necrosis 02/2012 - 02/2003
5	COVID-19 04/2022 - 01/2021
5	Infarction (Infarctions) 11/2021 - 11/2002
5	Disease Progression 01/2021 - 05/2005
5	Alzheimer Disease (Alzheimer's Disease) 06/2008 - 12/2002
4	Lymphopenia (Lymphocytopenia) 01/2022 - 05/2010
4	Neuroinflammatory Diseases 01/2022 - 09/2006
4	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2021 - 03/2011
4	Ulcerative Colitis 01/2021 - 03/2008
4	Dysbiosis 01/2021 - 02/2012
4	Colorectal Neoplasms (Colorectal Cancer) 10/2020 - 06/2011
4	Human Influenza (Influenza) 04/2016 - 12/2004
4	Glomerulonephritis 01/2016 - 06/2003

Drug/Important Bio-Agent (IBA)

78	CytokinesIBA 04/2022 - 01/2002
42	InflammasomesIBA 04/2022 - 06/2006
34	Proteins (Proteins, Gene)FDA Link 06/2021 - 03/2002
25	Interleukin-10 (Interleukin 10)IBA 01/2022 - 02/2006
25	Transforming Growth Factor beta (TGF-beta)IBA 12/2013 - 06/2002
21	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2015 - 07/2002
18	Interleukin-17 (Interleukin 17)IBA 12/2021 - 03/2003
17	AntigensIBA 01/2020 - 12/2002
16	Interleukin-18 (Interleukin 18)IBA 04/2022 - 02/2004
13	Interleukin-22 (IL-22)IBA 01/2021 - 10/2007
13	Phosphotransferases (Kinase)IBA 01/2021 - 06/2002
13	Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA 12/2013 - 09/2003
11	Messenger RNA (mRNA)IBA 01/2022 - 03/2002
10	Antiviral Agents (Antivirals)IBA 01/2022 - 12/2004
10	AntibodiesIBA 01/2022 - 06/2003
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2011 - 05/2003
10	p38 Mitogen-Activated Protein KinasesIBA 10/2009 - 06/2002
9	Interleukin-9 (Interleukin 9)IBA 01/2022 - 01/2002
9	RNA (Ribonucleic Acid)IBA 01/2022 - 12/2004
9	LigandsIBA 01/2022 - 05/2004
8	InterferonsIBA 04/2022 - 04/2009
8	InterleukinsIBA 01/2021 - 06/2006
8	Interleukin-6 (Interleukin 6)IBA 01/2019 - 02/2006
8	AutoantigensIBA 01/2016 - 12/2002
7	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 11/2002
7	Mitogen-Activated Protein KinasesIBA 06/2019 - 03/2003
7	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 03/2003
7	AutoantibodiesIBA 01/2016 - 09/2006
7	Insulin (Novolin)FDA Link 04/2014 - 08/2002
6	6-methyladenineIBA 01/2022 - 08/2018
6	Oxygen (Dioxygen)IBA 01/2019 - 11/2002
6	Caspase 3 (Caspase-3)IBA 11/2016 - 01/2003
6	NLR ProteinsIBA 06/2013 - 08/2009
6	Interleukin-12 (IL 12)IBA 04/2009 - 02/2004
5	ChemokinesIBA 06/2021 - 01/2007
5	Interleukin-4 (Interleukin 4)IBA 01/2021 - 01/2002
5	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2021 - 12/2010
5	Dextrans (Dextran)FDA Link 01/2021 - 12/2010
5	Interleukin-23 (Interleukin 23)IBA 01/2021 - 11/2006
5	LipidsIBA 01/2020 - 02/2006
5	VaccinesIBA 01/2019 - 07/2009
5	Interleukin-13IBA 01/2016 - 01/2002
5	Transforming Growth Factors (Transforming Growth Factor)IBA 07/2013 - 09/2003
5	Toll-Like Receptor 3IBA 11/2012 - 05/2004
5	Double-Stranded RNA (RNA, Double Stranded)IBA 11/2012 - 05/2004
5	Interleukin-1 Receptor-Associated KinasesIBA 09/2012 - 09/2006
5	Poly I-CIBA 02/2011 - 03/2006
5	Amyloid beta-PeptidesIBA 06/2008 - 12/2002
5	Transforming Growth Factor beta1 (TGF beta 1)IBA 05/2007 - 12/2002
5	CaspasesIBA 06/2005 - 03/2002
4	Viral RNAIBA 04/2022 - 06/2012
4	Interferon-gamma (Interferon, gamma)IBA 01/2022 - 06/2005
4	Immunoglobulin E (IgE)IBA 01/2021 - 01/2009
4	Pharmaceutical PreparationsIBA 11/2020 - 08/2003
4	CollagenIBA 06/2019 - 03/2003
4	Protein Isoforms (Isoforms)IBA 02/2016 - 03/2002
4	Transcription Factors (Transcription Factor)IBA 01/2016 - 08/2007
4	Pattern Recognition ReceptorsIBA 08/2013 - 02/2006
4	Oxidants (Oxidizing Agents)IBA 05/2013 - 12/2003
4	LipopolysaccharidesIBA 09/2012 - 07/2003

Therapy/Procedure

24	Therapeutics 01/2022 - 03/2003
10	Immunotherapy 12/2021 - 05/2004